Assessing parameter uncertainty in small-n pharmacometric analyses: value of the log-likelihood profiling-based sampling importance resampling (LLP-SIR) technique

Improved Methods for Pharmacometric Model-Based Decision-Making in Clinical Drug Development

Dosne, A.-G. 2016. Improved Methods for Pharmacometric Model-Based Decision-Making in Clinical Drug Development. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Pharmacy 223. 91 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9734-7. Pharmacometric model-based analysis using nonlinear mixed-effects models (NLMEM) has to date mainly been applied to learn...

Financial Modeling Using Sampling Importance Resampling"

While Bayesian methodology has been for decades widely applied to econo­ metric models, robust methods had just lately gained more attention of econo­ metricians. More recently, simulation-based techniques, such as the Sampling­ Importance Resampling (SIR) algorithm, have become useful and popular ap­ proaches to statistical problems. This article puts together the robust and Bayesian approache...

Assessment of a stochastic interpolation based parameter sampling scheme for efficient uncertainty analyses of hydrologic models

OF Assessment of a stochastic interpolation based parameter sampling scheme for efficient uncertainty analyses of hydrologic models Faisal Hossain , Emmanouil N. Anagnostou Department of Civil and Environmental Engineering, Tennessee Technological University, Box 5015, 1020 Stadium Drive, Cookeville, TN 38505-0001, USA Received 11 July 2004; received in revised form 10 October 2004; accepted 5 ...

Assessing Sampling Uncertainty in FVS Projections Using a Bootstrap Resampling Method

USDA Forest Service Proceedings RMRS-P-25. 2002 In: Crookston, Nicholas L.; Havis, Robert N., comps. 2002. Second Forest Vegetation Simulator Conference; 2002 February 12–14; Fort Collins, CO. Proc. RMRS-P-25. Ogden, UT: U.S. Department of Agriculture, Forest Service, Rocky Mountain Research Station. T. F. Gregg recently retired from the USDA Forest Service, Region 6 in Portland, OR. He was the...

On the convergence of quasi-random sampling/importance resampling